Adaptogens: What They Are, How They Work, and How to Choose One

Rhodiola rosea, an adaptogenic plant, flowering in the wild

"Adaptogen" has become one of the most-used words in wellness, and one of the least explained. It ends up on everything from coffee alternatives to gummies. But the idea behind it is specific, and once you understand it, choosing an adaptogen gets a lot easier.

Where the word comes from

The term was coined in 1947 by the Soviet pharmacologist Nikolai Lazarev to describe substances that help an organism resist stress in a general, non-specific way. In the decades that followed, his colleague Israel Brekhman and other researchers studied plants such as eleuthero and rhodiola, looking for ways to support stamina and resilience in athletes, soldiers and workers.

Out of that work came a working definition that herbalists still use. An adaptogen is a plant that:

  • helps the body handle many kinds of stress (physical, mental, environmental) rather than one specific problem,
  • tends to bring the body back toward balance instead of pushing a single system in one direction, and
  • is gentle enough to take consistently over time.

Many of these plants have far older histories, too. Ginseng, schisandra and reishi have been part of traditional Chinese practice for centuries, and ashwagandha and holy basil are cornerstones of Ayurveda.

How adaptogens are thought to work

Most research on adaptogens focuses on the body's stress-response system, the hypothalamic-pituitary-adrenal (HPA) axis, which governs cortisol and the "fight or flight" cascade. The general idea is that adaptogens help moderate how strongly and how long the body reacts to stressors, so you recover more smoothly instead of running on empty.

In practice, people describe the effect less as a jolt and more as steadiness: more even energy, a calmer baseline, better recovery after demanding days. That's also why adaptogens work best when taken consistently for several weeks. They're not a single-dose fix.*

Energizing vs. calming adaptogens

Adaptogens aren't interchangeable. A useful way to think about them is on a spectrum from stimulating to calming. Picking the right side of that spectrum matters more than anything else.

More energizing

  • Rhodiola (Rhodiola rosea). Grows in cold, high-altitude regions of Scandinavia, Siberia and the Arctic. Traditionally used for mental and physical stamina. Best taken earlier in the day.*
  • Asian ginseng (Panax ginseng). The classic "warming" tonic of traditional Chinese practice, used to support energy, stamina and cognitive function.*
  • Eleuthero (Eleutherococcus senticosus). The plant at the center of much of the original Soviet adaptogen research. Valued for endurance and for coping with long stretches of overwork.*
  • Cordyceps. A mushroom traditionally used to support stamina, exercise performance and lung function.*

Balanced, all-purpose

  • American ginseng (Panax quinquefolius). A cooler, gentler cousin of Asian ginseng, often a better fit for people who run hot or get wired easily.*
  • Schisandra (Schisandra chinensis). Called wu wei zi, the "five-flavor berry," in Chinese. Used to support mental performance and healthy liver function.*
  • Holy basil (Ocimum tenuiflorum). Known as tulsi in India. Used to help the body manage stress while promoting a sense of calm and focus.*
  • Gynostemma (Gynostemma pentaphyllum). Sometimes called jiaogulan, used to support the nervous and immune systems.*

More calming

  • Ashwagandha (Withania somnifera). The most popular calming adaptogen, traditionally used for people who are overtired and wound up at the same time.*
  • Reishi (Ganoderma lingzhi). A mushroom traditionally used to support the immune system and a settled, grounded state.*

How to choose

A simple way to start: be honest about what your stress looks like.

  • Tired, foggy, dragging through the afternoon? Lean toward the energizing side: rhodiola, eleuthero or Asian ginseng, taken earlier in the day.
  • Wired and tired: exhausted but can't switch off? Lean toward the calming side: ashwagandha or reishi.
  • Not sure, or want something for daily use? Start in the middle with American ginseng, schisandra or holy basil.
  • Training hard or physically demanding work? Look at rhodiola, cordyceps and eleuthero, or our Endure formula, which combines rhodiola, eleuthero, maral root, cordyceps, schisandra and licorice.*

If you'd rather not choose a single herb, formulas exist for exactly this. AdrenAlieve is our blend for the overworked and underslept. ImmuMend combines nine adaptogens, including astragalus, reishi, cordyceps, holy basil, Asian ginseng and schisandra, for long-term immune and stress support.*

How to take adaptogens

  • Be consistent. Most people notice the clearest difference after one to six weeks of daily use. Adaptogens build resilience gradually.
  • Mind the timing. Follow the label, but keep energizing adaptogens to earlier in the day, away from bedtime. Calming ones can be taken any time, including the evening.
  • Take breaks. Many herbalists suggest cycling, for example several weeks on and a week off.
  • Start with the label dose. Our extracts are measured by the dropper. Add it to a little water or juice, ideally between meals.

Adaptogens work best alongside the basics, not instead of them: sleep, real food, daylight and movement. No herb out-supplements a schedule that never lets you rest.

A note on safety

Adaptogens are generally well tolerated, but they are active plants. Talk to your healthcare provider before using them if you're pregnant or nursing, take prescription medication (especially for blood pressure, blood sugar, thyroid or mood), or have a medical condition. Stimulating adaptogens like Asian ginseng and rhodiola aren't a good fit late in the day.

Not sure where to start? Our master herbalist offers free consultations. Tell us what you're dealing with, and we'll help you find a fit.

Shop this guide: All adaptogens · Ashwagandha · Rhodiola · American Ginseng · Holy Basil · AdrenAlieve

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

Photo: Rhodiola rosea by sunoochi, licensed under CC BY 2.0.